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2019年12月13日 03:41:27    日报  参与评论()人

厦门腰腹部抽脂减肥新浪厦门哪个医院擅长做超声法去眼袋龙海做腋臭手术的费用 MOST people think of the empty space between the stars as being, well, empty. But it is not. It is actually filled with gas. Admittedly, at an average density of 100-1,000 molecules per cubic centimetre (compared with 100 billion billion in air at sea level), it is a pretty thin gas. But space is big, so altogether there is quite a lot of it.大多数人们认为星星之间就是空无一物,但事实并非如此。实际上有气体弥散其中。诚然,分子平均密度10^2-10^3/cm^3的气体非常稀薄(海平面处是10^26/cm^3)。不过由于空间很广阔,气体分子总体数量是可观的。Most of it, about 92%, is hydrogen. A further 8% is helium, which is chemically inert. But a tiny fraction—less than one-tenth of a percent—consists of molecules with other elements, such as oxygen, carbon and nitrogen, in them. Though these other elements are a mere soup#231;on of the interstellar soup, they do give it real flavour.大部分(约92%)的气体是氢,另外8%是惰性气体氦。还有一小部分(不超过千分之一)由氧、碳、氮等其他元素构成的分子。虽然这些元素仅仅是“星际浓汤”轻微的调料,但它们确实增添了汤的味道。Signs of life生命的迹象So far about 180 types of these molecular ingredients have been detected in space from their microwave spectra—the energy produced when molecules rotate around their chemical bonds. There are two reasons for wanting to study them. One is that these molecules are probably the precursors of life. The other is that the rarefied nature of astrochemistry changes the way processes work. It means the individual steps in chemical reactions can be disentangled from one another in a way that is hard—and sometimes impossible—on Earth. And it allows reactions to happen that are unknown on Earth.到目前为止,人们已经通过微波谱线探测出约180种分子成分。分子绕其化学键旋转时,分子能级会发生改变,从而产生微波谱线。研究微波谱线有两个原因。一是分子可能是生命的预兆。二是天体化学其稀薄的属性会改变化学反应的过程。人们可以用这种方式把化学反应中独立的一步从彼此步骤间分离出来,有时这在地球上很难实现。并且还有可能发生人类未知的化学反应。Now the astrochemists have a new tool: the Atacama Large Millimetre/submillimetre Array (ALMA) in northern Chile. It was officially opened on March 13th but has aly been making discoveries, including the most intense bursts of star birth in the early universe. ALMA consists of 66 dishes and is the world’s most powerful radio telescope. At a cost of .3 billion it should provide a hundredfold increase in sensitivity and resolution over the best older instruments.现在天体化学家有了新工具:阿塔卡马大型毫米/亚毫米波天线阵(ALMA,位于智利北部)。3月13日ALMA正式运作,到现在已经有了发现,例如宇宙早期恒星诞生最激烈的爆发。ALMA有66台天线,是世界上最强劲的射电望远镜。花费13亿美元想必会使灵敏度分辨率比过去最好的仪器还要好百倍。Those older telescopes had to focus on nebulae, where the interstellar gas is most concentrated (a familiar one, visible through binoculars, is the gas cloud around the stars that make up Orion’s sword). And older telescopes can detect only strong, simple signals of the sort emitted by small molecules like carbon monoxide and hydrogen cyanide, which have two and three atoms respectively. Spotting more complex substances was almost impossible because their rotational energy is scattered by their numerous bonds across a wide range of frequencies.以往的望远镜必须关注星云,那里是星际气体最集中之处。一个可用双筒望远镜看到的典例是气体环绕恒星所形成的猎户座的”剑”。并且老望远镜只能探测到一氧化碳(双原子)、氢氰化物(三原子)等小分子释放出的强的,简单的信号。而鉴别更复杂的物质几乎不可能,大量化学键占有很宽的频率范围,以至于旋转能被散射掉。ALMA, by contrast, can detect such things routinely. It has aly identified glycolaldehyde and acetone, molecules that have eight and ten atoms respectively. In particular, ALMA’s masters, a consortium of research agencies from Canada, Chile, Europe, Japan, Taiwan and the ed States, hope to find simple sugars and organic acids—molecules most researchers in the field believe were needed to get life going on Earth.相反ALMA可以轻易探测到这些信号:它已经鉴定出了乙醇醛(8原子分子)和丙酮(10原子分子)。特别的,由加拿大、智利、欧洲、日本、台湾及美国的财团组成的研究机构掌控ALMA,希望以此寻觅简单的糖类和有机酸——该领域大多数研究人员认为它们是地球上生命的必需之物。The ability to study chemical reactions stage by stage will be equally important. High-school chemistry lessons, with their neat equations transforming, say, 2H#8322; + O#8322; into 2H#8322;O, miss out a plethora of intermediate steps such as (in this case) the formation of hydroxyl, OH. In a lab, these intermediates are often too short-lived to be detectable. But in space an intermediate may hang around a long time before it encounters its partner in the next stage of a reaction. ALMA can see the microwave traces of such intermediates, and thus gain a better understanding of them.能够研究化学反应中的每一步同样很重要。高中化学课上简单的反应方程式省略了大量的中间步骤。例如2H#8322; + O#8322; 2H#8322;O就没有体现形成羟基(OH)的过程。实验室里,这些中间过程非常短暂,人们难以探测。不过在太空中,一个中间过程会持续很长时间,直到碰到下一步反应的搭档。ALMA可以看到这些中间过程的微波轨迹,因此研究者可以更好的了解这些过程。There are also completely new reactions to discover. Anthony Remijan, of America’s National Radio Astronomy Observatory, who is one of the astronomers putting ALMA through its paces, is studying the formation of methyl formate, a compound widely used on Earth in applications from insulation to insecticides. Usually it is synthesised either from methanol and formic acid, or methanol and carbon monoxide. But there is, in theory, a third route that uses formic acid and an unstable substance made from methanol and hydrogen. This has not been seen in an Earthly laboratory, but Dr Remijan thinks it is an important pathway in space, and ALMA should soon tell him if he is right.还有全新的反应有待人们发现。美国国家射电天文台的Anthony Remijan是将ALMA引入这个方向的天文学家中的一员。他正在研究甲酸甲酯的形成过程。从绝缘体到杀虫剂,可以说地球上到处都是甲酸甲酯。通常它由甲醇和甲酸,或甲醇和一氧化碳合成。但是在理论上,还可以使用甲酸和一种不稳定的物质来制造甲酸甲酯。(不稳定的物质则由甲醇和氢来形成。)这还没有在地球上的实验室中发现,但Remijan士认为在太空中这是一个重要的过程。ALMA应该很快就会告诉他他是否正确。Probably, that particular discovery will have no practical consequences. The known syntheses are effective, and methyl formate is aly cheap. But it will prove a principle about using the cosmos as a chemistry laboratory,and the hope is that similar findings about other molecules that are harder to make may allow chemical engineers at home to reformulate their processes.If that happens, the test tube in the sky really will have proved its worth.也许,上述特别的发现不会产生实用效果。甲酸甲酯熟知的合成方法很有效,而且它很便宜。但是,这明了一个理念:用宇宙充当化学实验室。希望有关其他较难制造的分子的类似发现能够让化学工程师在家里重新制定它们的合成过程。如果可以,天空中的试管确实有其价值。 /201303/231767Ben Bajarin#39;s ;reality distortion; theory about why Wall Street doesn#39;t get Apple (AAPL) -- first published in Time Magazine#39;s Techland last week -- has been widely picked up by numerous Apple watchers (including this one). But nobody has had more fun with it than Daniel Eran Dilger, a regular (and relatively straightforward) contributor to AppleInsider who likes to let it fly on Roughly Drafted Magazine, his personal blog.华尔街为什么不看好苹果公司(Apple)?本?巴加林在上周的《时代》杂志(Time)科技版上就这个问题撰文阐述了他的“现实扭曲力场”理论,被很多苹果观察家(包括笔者)广泛引述。AppleInsider网站长期撰稿人丹尼尔?伊兰?迪尔格心直口快,他对这个话题的兴趣比任何人都大,他甚至还在个人客Roughly Drafted Magazine上发表了文章以示持。Bajarin#39;s theory was that the magic by which Steve Jobs could spin almost anything his way has been reversed; now the perception on the Street and in the media is that Apple -- whose main problem, according to Bajarin, is that it can#39;t make smartphones and tablets fast enough to meet demand -- is doomed.巴加林的理论是,史蒂夫?乔布斯扭转乾坤的魔力已经被人逆转了。巴加林认为,如今华尔街和媒体界普遍认为,苹果的主要问题是无法迅速生产出足够多的智能手机和平板电脑来满足市场的大量需求,苹果劫数难逃。Dilger has refined Bajarin#39;s theory and identified what he believes to be the source of the new distortive power. He calls it ;flexibly adaptive logic.;迪尔格进一步完善了巴加林的理论,提出了他眼中的全新逆转力量的源泉所在——他把它称为“灵活的自适应逻辑(flexibly adaptive logic)。”(即后文所说的“逻辑缺陷”——译注);Flawgic,; he writes, ;is neither hardware nor software; it#39;s installed directly into public mindshare via a virus sp by talking heads.;他写道:“逻辑缺陷(flawgic)并不是硬件或软件的问题,而是在人们的日常交流中,以口碑传播的方式,像病毒一样迅速蔓延,最终深深植根到公众心目中。”For example:例如:;If Apple were to release a cheap iPhone that cost or a luxury one that cost 00, it would receive intense scrutiny in either direction. The cheap version would be derided as flawed and worthless, while the expensive version would be laughed at for being ludicrously priced.“不论苹果要发布一款价格50美元的廉价款iPhone,还是一款价格2,000美元的豪华款iPhone,都会遭到严厉的批评。廉价款会被数落为粗制滥造;而豪华款则会由于高昂的价格遭到嘲笑。;Flawgic allows low end Android products to be hailed as volume sales generators, even if they are terrible products in every way. But it also does double-duty in allowing Google#39;s insanely priced devices, from Glass to Chromebook Pixel, to escape criticism of their inherently poor overall value or the likelihood of their ever selling in meaningful volumes.;“由于这种逻辑缺陷,即使低端的安卓产品从各个方面来看都很糟糕,还是被誉为走亲民路线的销量王。它还为谷歌(Google)提供了双重帮助:使从谷歌眼镜到Chromebook Pixel这样整体价值低劣、价格却贵得离谱的设备免遭诟病,还让这些设备大卖特卖变得可能。”他说,逻辑缺陷就是这么强大。Dilger really hits his stride when he talks about how the Flawgic gene was passed to Samsung, allowing it to argue with a straight face in federal court that it -- not Apple -- was the patent infringement victim.谈到逻辑缺陷这种基因如何传给三星(Samsung)时,迪尔格更是亮出了鲜明的观点。逻辑缺陷让三星敢于在联邦法院上一脸严肃地争辩称,它自己——而非苹果——才是专利侵权的受害者。;It#39;s like a rapist saying he had penetrated against his own will,; writes Dilger, ;and please lock this woman up before she is allowed to have forcible sex with other innocent rapists. And can I sue her for damages? I think I hurt my penis.;迪尔格说:“这就好比一个强奸犯说,发生性行为违背了他本人的意愿。放任这位女士与其他无辜的强奸犯发生强制性行为之前,请把她关起来。另外,我能不能起诉她,要求损害赔偿?因为我觉得我的性器官受到了损伤。”There#39;s more of the same at Google#39;s Android powered by remarkable new ;flexibly adaptive logic;这种非凡的、全新的“灵活的自适应逻辑”对谷歌安卓系统的撑更是有过之而无不及。 /201303/230704厦门伊藤痣哪家好

同安区开双眼皮哪里好在厦门假体丰胸术哪家好 Mike Senna, a computer programmer from Orange County, California, has spent the last two and a half years building a real-life Wall-E robot, from scratch. It moves around, rolls and talks, but he doesn#39;t collect trash.经过了两年半的努力,来自加州奥兰治县的电脑程序设计师麦克-森纳终于造出了一个真实版的机器人瓦力。它能动,能绕圈,能说话,不过还不会收集垃圾。In 2009, shortly after the movie Wall-E was launched, we featured some photos of cool Wall-E computer case mod, but that feat simply pales in comparison to Mike Senna#39;s awesome achievement.2009年,电影《机器人瓦力》上映不久,我们曾拍到过几张用电脑机箱搭建的瓦力照片。但在森纳所取得的无以伦比的成就面前,这些照片显得异常苍白。The robot aficionado spend between 3,200 and 3,800 man hours building his very own version of the adorable Pixar trash-collecting hero. His computer programming skills definitely came in handy, but seeing as there were no Wall-E parts available anywhere on this planet, he had to construct the whole thing from scratch. He worked on it about 25 hours a week, after his day job, but all the hard work certainly paid off.这个机器人狂人花费了3200到3800工时,来建造这个独一无二版的热衷于垃圾收集的皮克斯动画可爱主人公。森纳的计算机程序设计技术无疑派上了用场。不过鉴于在这个世界上还没有任何类似瓦力的存在,这一切都必须从零开始设计。森纳每天在白天的工作后开始动手制作瓦力,每周在这上面花费25小时,终于这辛苦的劳作获得了成功。This isn#39;t Mike Senna#39;s first robot, either. In 2003, he created his own version of R2D2, so he#39;s pretty well-known in select geek circles. His latest creation has started making appearances at various events, putting a smile on children#39;s faces and getting praised by adult geeks.这并不是森纳制造出的第一个机器人。2003年,他制造出了专属的《星球大战》中的R2D2机器人,因而在技术宅们的小众圈子里已经小有名气。这次他最新造出的真实版瓦力已经开始在各种场合登场得孩子们一笑,这同样也赢得了很多成年电脑迷的赞赏。 /201208/193996厦门市欧菲整形在那

厦门鼻部整形哪家医院好RON DEPINHO is a man on a mission. Oddly, though, he does not yet know exactly what that mission is. Dr DePinho is the new president of the MD Anderson Cancer Centre in Houston, Texas. (He took over in September, having previously headed the Belfer Institute, part of Harvard#39;s Dana-Farber Cancer Institute.) Mindful of his adopted city#39;s most famous scientific role, as home to Mission Control for the Apollo project, he says his own mission is akin to a moon shot. He aims to cure not one but five varieties of cancer. What he has not yet decided is: which five?罗恩bull;徳平厚肩负着一个使命。虽然奇怪的是,他现在仍不清楚他的使命的确切目标是什么。徳平厚士是德克萨斯州休斯顿市的MD bull;安德森癌症研究中心的新任主任,他此前是哈佛的丹娜-法波尔癌症研究院下属的贝尔佛研究所所长。徳平厚知道,休斯顿在科学领域最广为人知的,是其作为阿波罗登月计划的目标控制中心所在地。因此,他说他自己的目标也类似于登月。这就是,要找到攻克不仅一种,而是五种癌症的方法。他现在还没有决定的是哪五种癌症。That it is possible to talk of curing even one sort of cancer is largely thanks to an outfit called the International Cancer Genome Consortium. Researchers belonging to this group, which involves 39 projects in four continents, are using high-throughput DNA-sequencing to examine 50 sorts of tumour. They are comparing the mutations in many examples of each type, to find which are common to a type (and thus, presumably, causative) and which are mere accidents. (The DNA-repair apparatus in malignant cells often goes wrong, so such accidents are common.)现在,人们之所以敢于谈论攻克癌症(即便是其中一种癌症),主要是因为一个名为国际癌症基因图谱研究联盟的组织。这个组织包括遍布四大洲的39个研究项目,该组织的研究人员使用高流量的基因测序方法来检测50种不同的肿瘤。他们把每种肿瘤的众多基因突变案例进行比较,区分出对某种肿瘤来说,哪些突变是共同的(从而,估计是致病原因),哪些突变是偶然的(恶性细胞中的基因修复机制经常出错,所以偶然突变是常见的事)。The consortium#39;s work is progressing fast, and preliminary results for many tumours are aly in. But such knowledge is useless unless it can be translated into treatment. That is where Dr DePinho comes in;for his career has taken him into the boardroom as well as the clinic. He is a serial entrepreneur: he helped found Aveo Pharmaceuticals, which is developing a drug to block the growth of blood vessels in tumours, Metamark Genetics, which works on diagnosing cancers, and Karyopharm Therapeutics, which is trying to regulate the passage of molecules into and out of the cell nucleus, and thus control the nucleus#39;s activities. His aim in coming to MD Anderson, he says, is to ;industrialise; other aspects of biological research in the way that genetics has been pushed forward by high-throughput sequencing.这个联盟的工作进展很快,已经得出了很多种肿瘤的初步研究成果。但是,对病因的认知只有转化为治疗方法才是真正有用的。这正是徳平厚士要做的事,因为在他的职业生涯中,他既做过诊疗工作,也做过经营管理工作。他是一个富有经验的企业家,参与创建过若干个公司,包括:正在研制阻碍肿瘤中血管生长的药品的Aveo制药公司;研究癌症诊断方法的Metamark遗传研究公司;还有Karyopharm 诊疗研究所,这个所的研究方向是,通过控制分子进出细胞核的方法来控制细胞核的活动。他说,他来MD bull;安德森癌症研究中心的目的是,以高流量测序推动遗传研究的同样方式,用;产业化;的方法来推动生物学领域其它方面的研究。That will cost billions of dollars. Fortunately, the state of Texas;no pushover when it comes to spending taxpayers#39; cash;is creating a billion cancer-research fund to help pay for it. Local philanthropists, including T. Boone Pickens and Ross Perot, are chipping in, too. Their model is the original Human Genome Project, during which the cost of sequencing a single genetic ;letter; (a DNA base pair) fell from in 1991 to ten cents in 2001;and is now 3,000 base pairs a cent. They hope their dollars will encourage people working with what are now, essentially, craft technologies to think about how they might industrialise them.他的计划将花费数十亿美元。幸运的是,尽管德克萨斯州在花纳税者的钱上是非常谨慎的,但已经建立了一个30亿美元的癌症研究基金来持这个计划。当地的慈善家,如T. Boone Pickens 和 Ross Perot等也给与了持。他们的模式和原先的;人类基因图谱项目;相同,在那个项目中,单个DNA碱基的测序价格从1991年的10美元降到2001年的1毛钱,现在是3,000个碱基1分钱。他们希望,他们的资金将鼓励那些现在基本上是运用手工技术的研究人员,考虑如何把那些技术产业化的问题。Several techniques look ripe for such industrialisation. Dr DePinho sets great store, for example, by the use of genetically modified mice (he calls them ;little patients;) in which mutations found in human cancers can be replicated precisely, but one at a time, to discover the shape of each piece of the jigsaw. If this process can be scaled up it will, as he puts it, allow cancer#39;s genetic generals to be distinguished from the foot soldiers.对于这种产业化方式,若干技术看来已经相当成熟。例如,徳平厚士很重视运用基因被改造过的老鼠(他称之为;小患者;),研究者把人类癌症的基因突变精确地复制到这些老鼠身上,从而发现这些突变的基因图谱每一部分的形状。但是,基因突变的复制只能一次做一个,他认为,如果这个过程可以成规模地来做,就可以区分基因突变的主因和偶然事件。Another field that has great potential is imaging technology;in particular, a combination of (which uses radioactive sugar to measure how metabolically active tissue is) and computerised tomography (which uses X-rays to map the body#39;s internal anatomy). Together these can show whether a treatment is reducing a cancer#39;s energy consumption, and thus its metabolism. This gives a good indication of how well that treatment is working.另一个很有希望的领域是成像技术,具体说,这是两种技术的结合:正电子放射层扫描术(用放射性糖来测量细胞组织新陈代谢的活跃程度),和电脑化的体层摄影技术(用X-射线来绘制人体内部的解剖结构)。两种技术一起运用,可以显示某种治疗方法是否降低了肿瘤的能量消耗,从而是否减缓了它的新陈代谢。这对于评价治疗方法的有效性很有帮助。A family businessDr DePinho himself will have more duties at MD Anderson than just dealing with the five chosen tumours. The donkey work of creating the Institute for Applied Cancer Science, as the new mission control is to be known, will be done by Lynda Chin. Dr Chin, too, worked at the Belfer Institute. She is part of the International Scientific Steering Committee of the cancer-genome project. And she is also Dr DePinho#39;s wife. Dr Chin will be assisted by some 55 other scientists from the Belfer, who are making the journey to Texas with her and her husband. That sort of team poaching is common in investment banking but rarer in academic research. Dr DePinho refers to it, jokingly, as metastasis, since a clone of his primary creation will be taking root elsewhere in the country.夫妻店生意徳平厚士在MD安德森的作用远不止确定哪五种肿瘤。建立肿瘤应用科学研究所(这是新的目标控制机构的名称)的艰苦工作是琳达bull;秦的责任,她也曾在贝尔佛研究所工作。她还是癌症图谱项目的国际科学指导委员会的成员,并且是徳平厚士的妻子。55名科学工作者将和徳平厚夫妇一起从贝尔福来到德克萨斯,帮助秦士工作。这种挖走人家整个团队的做法在投资界司空见惯,但是在学术研究界却不多见。徳平厚士把此事戏称为;细胞转移;,因为他原先创造的研究机构的克隆物将在另一个地方扎下根来。As to which five cancers to attack, that decision will be made by the middle of 2012. A crucial consideration will be how likely it looks that research into the tumour in question could get rapidly to the ;proof of concept; stage;the point at which it could be taken forward by a business that relied on commercial sources of capital, rather than on the sorts of grants that usually propel academic research. At that moment a new firm might be spun out of the institute, or a deal might be done with an established pharmaceutical firm, to try to get a new drug developed.至于把哪五种癌症作为目标,将在2012年年中决定。一个关键因素是看对目标癌症的研究是否能尽快达到;概念验;的阶段,到了那个阶段,研究工作就可以在商业资本的持下作为一个生意来向前推进,而不是仅仅是依靠科研拨款。这样,或者可以在研究所的基础上成立一个新公司,或者可以和既有的制药公司合作,从而研发一种新药。In recent years many big drug companies have gutted their research departments. This is partly because those departments have failed to come up with new ;blockbuster; drugs of the sort that created Big Pharma in the first place, and partly because the big firms#39; bosses had hoped that smaller biotechnology companies, of the sort Dr DePinho has helped set up, would do the hard work of drug discovery instead, and then let themselves be bought by the big firms.最近这些年来,很多大制药公司取消了他们的研究部。部分原因是,这些研究部没能研制出当初做大这些大制药公司的拳头产品那种量级的新产品,部分原因是,那些大制药公司的老板们希望徳平厚士那样的小生物技术公司承担发明新药的艰巨工作,然后再把这些小公司收购进来。Unfortunately, it hasn#39;t quite worked out like that. The output of the biotech firms has been a trickle, rather than a torrent. They have been one of the worst-performing parts of the private-equity market since 2007, according to Dr DePinho. He hopes to change that;and in the matter of new anti-cancer drugs, the science is looking auspicious. For example, a drug called vemurafenib, which was approved for use in America in August 2011, gives months of extra life to people with metastasising melanoma, one of the deadliest cancers. Vemurafenib is so powerful that some people call it a ;Lazarus; drug, after the chap Jesus is said to have raised from the dead.令人失望的是,事情并没有像他们设想的那样发展。生物技术公司只有一些点滴的成果,没有产生什么大的成果。徳平厚士指出,自2007年以来,这个领域是私募股份市场上表现最差的领域之一。他希望改变这个局面。而研制抗癌新药的科技看来正处于幸运期。例如,2011年8月,美国批准了一种名为vemurafenib的新药,它可以把最恶性的癌症之一黑色素瘤病人的生命延长数月。这种药的效力是如此显著,以致一些人把它称为;拉扎罗斯;;; 那个被耶稣起死回生的麻风病人的名字。Crucially for Dr DePinho#39;s project, the development of vemurafenib was stimulated by the identification of a mutated gene often present in melanomas. He and others like him hope that the cancer-genome consortium will throw up dozens of similar genes, and that they, too, will prove tractable targets for drug development.对徳平厚士很有意义的是,vemurafenib的研发正是由于辨识了经常出现在黑色素瘤中的一种突变基因所推动的。徳平厚和同行们希望癌症基因图谱研究联盟能够发现几十种类似的基因,从而能够为新药研发提供可控的目标。Of course, if Dr DePinho had a penny for every time a ;cure for cancer; headline proved premature, he wouldn#39;t need munificent donors. But if his bets on the science and on adopting business methods pay off, the drug industry and millions of patients will benefit. That would be one benign sort of metastasis.当然,过去已经有太多关于;攻克癌症;的宣告最终被明是为时过早。[注]但是,如果徳平厚士的科研选题和运用商业方式的办法能够奏效,制药行业和数百万患者将会受益。那倒真可以称之为一个良性的细胞转移。 /201201/168407 福建厦门第三人民医院网站福建省第二医院激光脱毛多少钱

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